Study: Early ICU requirement linked to elevated risk of future infections in Covid-19 patients | – Times of India


PUNE: A recent collaborative study conducted by multiple healthcare institutions, including Deenanath Mangeshkar Hospital and Research Centre in Pune, has shed light on secondary infections (SIs) among Covid-19 patients, potentially complicating the clinical course and worsening outcomes.
The study, which aimed to analyze the incidence and risk factors associated with SIs in individuals diagnosed with Covid-19, utilized data from 731 hospitalized patients at Milan’s Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), San Raffaele Hospital, between February and April 2020.
Secondary Infections (SIs) refer to infections that occur in addition to the initial Corona Virus Disease 2019 (Covid-19) infection. These SI can be caused by bacteria, fungi, or other viruses and they can complicate the clinical course of the disease, leading to worse outcomes. The purpose of the study was to describe the incidence as well as danger factors for SIs in people with Covid-19 diagnoses.
Study found that infections with gram-positive bacteria, particularly coagulase-negative staphylococcus have been accountable for most bloodstream infections, but gram-negative pathogens, such as Acinetobacter baumannii and Escherichia coli, were less frequent.
Eleven people were identified in the investigation as possibly suffering from significant aspergillosis. Following the very first 48 hours following residential therapy, the individual was brought to the Intensive- Care Unit (ICU) due to an insufficient initial lymphocytes level. “The finding that early need for ICU has been connected to a higher chance of developing infections in the future highlights the importance of prompt and appropriate treatment for individuals with serious Covid-19,” the study said.


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